Advil and coffee are two of the most commonly ingested drugs, yet many people have questions regarding the potential health effects of taking Advil and drinking coffee in close succession. The answer to whether or not one can take Advil and drink coffee directly afterwards is based upon underlying health issues and medications; individuals should consult their healthcare provider for specific health advice for their individual situation.
Though Advil is one of the most commonly used over-the-counter pain relievers, caffeine may reduce the effects of ibuprofen if one takes Advil and drinks coffee within two hours of each other. In addition to ibuprofen, caffeine can also reduce the efficacy of certain blood pressure medications such as clonidine and verapamil; thus, one with a history of high blood pressure may want to limit consumption of caffeine when taking Advil.
The relationship between Advil and coffee may be further complicated by the fact that coffee, which contains caffeine, is a diuretic. Diuretics are substances that cause the kidneys to produce urine more quickly, and the increased urinary frequency may lead to dehydration. While dehydration can be avoided with proper hydration throughout the day, there is evidence that dehydration can increase the risk of adverse effects when taking ibuprofen, including irritation to the stomach.
Moreover, experts suggest that Advil and coffee can interfere with each other’s pharmacological effects due to Advil’s properties as a non-steroidal anti-inflammatory (NSAID). NSAIDs, including Advil and ibuprofen, can produce a variety of symptomatic and clinical effects. One of Advil’s mechanisms of action is that it inhibits prostaglandin synthesis, which is the body’s natural way of protecting the stomach from acid. Caffeine, however, is known to increase the production of stomach acid and reduce the effectiveness of Advil.
Caffeine and Advil also block the transportation of drugs to different parts of the body. For instance, when caffeine is taken in combination with an oral contraceptive, it can reduce the body’s absorption of it up to 70%. Similarly, Advil and caffeine can lower the absorption rates of many other drugs, including those prescribed by healthcare professionals to treat high cholesterol, arthritis and other inflammation-related diseases. As such, people who take Advil and drink coffee should be aware of potential interactions with other medications they take.
Overall, it is important to be aware of the potential effects of taking Advil and drinking coffee. Generally, if one consumes coffee and Advil at least two hours apart, one can limit the risk of any adverse effects and interactions. However, it is important to note that individual reactions may vary, so it is best to consult your healthcare provider for specific health advice for your individual situation.
Caffeine and Dehydration
Caffeine, which is present in coffee, is a diuretic, meaning that it can make one urinate more frequently and should be used with caution when taking Advil. The increased urination caused by caffeine can lead to dehydration and individuals should be careful to stay properly hydrated when consuming caffeine with Advil. While water is the best hydration method, electrolyte-rich options such as sports drinks, coconut water and even some fruits, like oranges and limes, can be helpful in re-hydrating the body during times of increased caffeine and taking Advil.
Interactions with Other Medications
It is important to remember that taking Advil and drinking coffee near one another can lead to interactions with other medications. It is highly recommended that people consult the label on any prescription medications they are taking before combining with caffeine. Advil and caffeine can reduce the absorption rates of certain drugs, including those prescribed by healthcare professionals to treat high cholesterol, arthritis, and other inflammation-related diseases.
Determining Individual Risks
Individuals should take into consideration their underlying health issues when determining whether or not to take Advil and drink coffee at the same time. Factors such as age, weight and overall health may be important in determining whether it is safe to combine Advil and caffeine. In general, it is best to consult with a doctor if any questions or concerns arise regarding taking Advil and drinking coffee; this will help to ensure safety and maximise the effectiveness of both Advil and caffeine.
Influence on Mental Health
Caffeine can have a profound influence on mental health and alertness. In addition to providing energy, caffeine can also improve concentration, reduce fatigue and improve mood. However, excessive amounts of caffeine can also lead to anxiety, irritability, and insomnia. It is important to be aware of one’s tolerance for caffeine as this can greatly influence one’s reaction when taking Advil and drinking coffee.
Potential Side Effects
Though Advil and caffeine are both generally considered safe when taken individually, there are potential side effects when combining the two. For example, those who take Advil and drink coffee in close succession may experience an increased risk of stomach irritation, dizziness, headache, and nausea. Individuals who experience any of these symptoms should contact their healthcare provider to ensure their safety.

